Why does the deamination of cytosine to uracil not cause a problem in the next round of DNA replication?
A) Although uracil cannot form the third hydrogen bond to guanine, it is recognized by DNA polymerase as a mismatch and the error is corrected on the next round of replication.
B) The AP endonuclease nicks the backbone and removes the uracil and replaces it with cytosine.
C) The repair machinery recognizes uracil in DNA as a mistake and replaces it with cytosine.
D) The uracil undergoes spontaneous depurination and is replaced with cytosine.
E) Deamination of cytosine rarely occurs within the coding region and so causes few mutations.