Compared to previous theories, what is the most novel or revolutionary idea proposed by the neuromatrix theory of pain?

A. The pain experience is affected by cognitive and emotional input.
B. The pain signal is produced not only at the site of tissue damage, but also in the brain and spinal cord.
C. Sensory input is only one of multiple types of input affecting the pain experience.
D. Pain is produced in the central nervous system.
E. The pain experience involves multiple components of the central nervous system.