Which statement best describes the use of polygenic risk scores in making illness/disease predictions in populations?
a) Copy number variants (CNV) from a genome-wide association (GWAS) study of an illness/disease risk of one population are used to make predictions of illness using algorithms in another group.
b) Single nucleotide base changes in one gene from a genome-wide association (GWAS) study of an illness/disease risk of one population are used to make predictions of illness using algorithms in another group.
c) Gene expression changes (i.e., methylations) in multiple genes from a genome-wide association (GWAS) study of an illness/disease risk of one population are used to make predictions of illness using algorithms in another group.
d) Single nucleotide base changes in multiple genes from a genome-wide association (GWAS) study of an illness/disease risk of one population are used to make predictions of illness using algorithms in another group.