The nurse is giving the client a per-rectum (PR) enema containing an emollient/lubricating laxative. What adverse effects should the nurse be aware of when administering this medication?
1) Gastrointestinal (GI) disturbances such as bloating, flatulence, cramping, and nausea
2) Rectal irritation
3) Increased white blood cell count (WBC)
4) Decreased absorption of vitamins A, D, E, K
5) Fluid and electrolyte loss