A particular enzyme is not active until a cofactor binds to the substrate binding site. Which of the following is true? (three answers are correct)
A. This describes a holoenzyme / apoenzyme
B. The cofactor could be something like a vitamin or a metal ion
C. The cofactor is also called the substrate
D. By controlling the amount of cofactor the cell would be able to control the amount of product made by the enzyme
E. This describes an allosteric enzyme