Phenytketonuria (PKU) is due to an autosomal recessive mutation (k). People who are carriers for this mutation are present in the population at a frequency of 1/40,000. Assume that a person does not have PKU unless this is explicitly stated in the question. Paul marries Jean, whose maternal grandmother had PKU, and they want to have a child. Assume that Jean's father and paternal grandfather are homozygous wild type (KK).
Based on this information, select the answers that are MOST LIKELY to be TRUE. Select 3 correct answer(s)
a) The probability that Jean is heterozygous for the PKU mutation (Kk) is 1/40,000.
b) The probability that Paul and Jean's first child will have PKU is 1/4.
c) The probability that Jean is heterozygous for the PKU mutation (Kk) is 1/2.
d) The probability that Paul is heterozygous for the PKU mutation (Kk) is 1/40,000.
e) The probability that Jean is heterozygous for the PKU mutation (Kk) is ¼.
f) The probability that Paul and Jean's first child will have PKU is 1/320,000.
g) The probability that Paul is heterozygous for the PKU mutation (Kk) is 1/2.
h) The probability that Paul and Jean's first child will have PKU is 1/160,000.