All of the following are problems that result from the use of pesticides except (a) pesticide run-off enters surface waters and increases the solubility of heavy metals. (b) most inert ingredients are not tested for safety and may pose unacceptable risks. (c) most pesticides are not target specific and kill other related and nonrelated species. (d) pesticides affect nontarget organisms by changing community relationships. (e) pesticides target specific physiological functions but also disrupt other functions.