Which of the following statements regarding heme are TRUE?
A. Heme is a prosthetic group only for the protein hemoglobin. cross out
B. Heme binds to hemoglobin only by hydrophobic interactions. cross out
C. Hemoglobin can weakly bind oxygen even without a bound heme. cross out
D. The iron in heme is only able to bind oxygen. cross out
E. Heme is amphipathic. cross out
F. None of the above are true.