A 0.625 g of paracetamol powder with a uniformly sized particles was dissolved in 1000 ml of water. The dissolution data are found in the table below.
Determine the value of k, the cube-root dissolution rate constant, at each time interval and calculate the average value of K.
T(hr)
Concent. Drug release mg/ml
Amount drug release Mg/1lt Wt
0
159
Amount of undissolved drug Mt-625-Wt
0
0
0.159
466
4
0.288
0.39
288
337
6
8
390
235
0.468
0.528
468
157
10
528
97