A mitochondrial mutation leads to ataxia (loss of coordination), muscle weakness, and retinal degeneration. Tissue biopsies were taken from 4 patients with this disease and mitochondrial particles were isolated. The ability of the mitochondria to synthesize ATP from succinate was found to be not significantly different from the controls. ATP production in the absence of succinate was significantly reduced compared to the controls. Which is the likely location of the mutation?
a. Complex III
b. ATP synthase
c. Complex II
d. Complex IV
e. Complex I