Which of the following statements is true regarding the use of medications during breastfeeding?
a. Drugs with high lipid solubility are safe because they do not appreciably enter breast milk.
b. Medications with high molecular weight can pass to breast milk only during the neonatal period.
c. The safest time to breastfeed is at tmax, because then, drug plasma concentration is maximal and drug concentration in breast milk is therefore, minimal.
d. Medications with high protein binding pass easily to breast milk.