Ebonee Parker, age 9, is admitted to the oncology unit for chemotherapy for acute lymphocytic leukemia. Weight is 60 pounds, height is 60 inches, BSA 1.05. (Topics covered: converting pounds to kilograms, determining a safe dose, mg/kg calculations, body surface area calculations)

Medication orders:
· asparaginase 27,000 international units in 50 mL D5W, IVPB. Infuse over 30 minutes
· prednisone 15 mg po q 8 hours
· vincristine 2 mg in 50 mL D5W, IVPB. Infuse in 15 minutes
· morphine 1.5 mg IVP q 6 hours prn pain
· dexamethasone 4 mg IVP bid
· ondansetron 4 mg IVP 30 minutes prior to chemotherapy, repeated 4 and 8 hours later
· Primary IV: D5W 50 mL/hour × 24 hours
Calculate the safe dose, determine if the ordered dose is safe, and calculate the amount needed for the correct dose (round the weight conversion to a whole number; do not round answers unless directed):
asparaginase. Safe dose: 25,000 international units/m2 3 times a week. Supply: 10,000 units/mL. What is the infusion rate?



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