Sudden Infant Death Syndrome (SIDS) Sudden infant death syndrome, or SIDS, was first rec- ognized as a distinct public health problem in the late 1960s when over 7000 infants each year were found to die suddenly and unexpectedly. "Crib deaths" have been recognized for centuries, but until they were formally recorded and investigated, little was known about their cause, leading some to conclude that intentional or unintentional suffocation by parents or caregivers played an important role. Data from the investigations of SIDS indicated that the syndrome was very rare before babies' first month of life, increased during the second month, and peaked during the third month, before rapidly declining in frequency to again become rare after the fourth month of life. The timing of SIDS suggested that the condition occurs after infants begin to sleep for extended periods but prior to the time in which children can raise themselves up and roll over on their own. Additional evidence suggested a seasonal trend, with more cases of SIDS occurring during cold weather months than during warm weather months. In the 1980s, several case-control studies of SIDS cases and similar infants without SIDS established that infants who slept on their stomachs were at substan- tially increased risk of dying from SIDS. The studies indicated that the chances increased 4-7 times, sug- gesting that if a cause-and-effect relationship exists, a clear majority of SIDS cases could be prevented if infants slept on their back. Many parents and cli- nicians remained skeptical because the traditional teaching emphasized sleeping prone, or on the stom- ach, to reduce the possibility of choking on regurgita- tion and vomit. Despite the lack of evidence for this hazard, generations had been raised on this practice and belief. Additional evidence of the effectiveness of a "back- to-sleep" intervention was provided by the experience of New Zealand, which was the first country to begin a program to encourage caretakers to put infants to sleep on their backs. The rates of SIDS in New Zealand declined rapidly in parallel with the increased rate at which infants were put to sleep on their back. Similar declines in SIDS did not occur in other countries that had not yet instituted similar back-to-sleep programs. In 1992, the American Academy of Pediatrics made a recommendation that infants be placed on their back to sleep. The initial recommendations also endorsed side sleeping. In 1994, with the support of the American Academy of Pediatrics, the National Institutes of Health (NIH), and the U.S. Public Health Service, the Back-to-Sleep campaign was launched. The educational campaign included public service announcements, brochures and other publications, including information accompanying new cribs, plus efforts for pediatricians and others who care for infants to educate parents and caretakers about the importance of having infants sleep on their backs. The frequency of infants sleeping prone in the United States was found by curvey data to be reduced but less than expected by the initial data. The rate of prone sleeping among African Americans was found to be over twice as high as the rate among whites, and African American infants continued to have higher rates of SIDS than whites. Continuing studies suggested that the side posi- tion was being commonly used. It was found that many infants moved from the side to the prone position, and movement from the side to the prone position carried a high risk of SIDS. Additional case-control studies suggested that soft objects and loose bedding as well as overheating were associated with SIDS. These rela- tionships are consistent with the initial finding of an increase of SIDS in colder weather months. Studies of the infants who slept on their back indicated an increasing in flattening of the head, or plagiocephaly. These changes were shown to be reduced by increasing the amount of "tummy time." or play periods in which infants are placed prone under supervision. Guidelines for tummy time are now part of the evidence-based recommendations. SIDS continues to be an important cause of infant mortality, and new contributory causes continue to be investigated. SIDS reflects the use of evidence-based public health and the importance of continuing to study and develop new approaches to public health problems. Discussion Questions 1. 2. Discuss how the problem description com- ponent of the evidence-based public health approach suggested hypotheses for the etiology of SIDS. Discuss the types of evidence used to support the relationship between sleeping prone and SIDS as well as the limitations of the evidence.
1. Discuss how the evidence-based recommenda- tions incorporated potential benefits and harms.