During the workshop, we discussed two different scenarios involving apoptosis.

One scenario presented a case of chronic heart disease. If you are trying to develop a drug that could cure chronic heart disease, which of the following targets would be most appropriate while limiting the number of side effects?

a) Downregulate the production of cytochrome C
b) Upregulate the production of IAPs
c) Downregulate Bcl2
d) Downregulate caspase 8
e) Downregulate the production of IAPs and upregulate Bax
f) Upregulate caspase 8
g) Upregulate the production of cytochrome C