This article investigates whether perceived interpersonal discrimination plays a role in the link between disability and mental health (depression, negative and positive affect), as well as how these processes change over the course of a person's life. The information comes from two waves of the Midlife in the United States (MIDUS) survey, which had 2,503 people in each wave (2004-2006 and 2013-2014). Five to eight percent of the link between disability and the three mental health outcomes is due to perceived discrimination. Moderated mediation analyses show that there are big differences between the ages of the people analyzed. Perceived discrimination is a stronger predictor of behavior in adults in midlife (ages 40-64) compared to older adults (ages 65+). At midlife, when adults are expected to be able-bodied and have a wide range of friends who may treat them badly because of their disability, the psychological effects of disability stigma are at their worst. For older people, who are more likely to have impairments, the mental effects of disability may happen in different ways. We talk about what this means for practice and research. Questions:
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