In what way does an uncompetitive inhibitor bind to an enzyme?
A. It reversibly binds to the enzyme active site.
B. It reversibly binds to both the free enzyme and the enzyme substrate complex.
C. It irreversibly binds to an enzyme allosteric site.
D. It irreversibly binds to the enzyme active site.
E. It reversibly binds to the enzyme substrate complex but does not bind to the free enzyme.