Epilepsy has been described as an "electrical storm" in the brain. This can happen when there are too many excitable messages or not enough inhibitory ones. Which of the following ion and/or neurotransmitter problems could lead to a seizure?
A. Decreased GABA levels
B. Increased release of glutamate
C. Decrease in Cl- entrance or a decrease in the K+ current leaving the neuron
D. Increased Na+ or Ca++ entry into the neuron
E. All of the above could make a neuron more excitable, which could lead to a seizure.