A patient who is 27 weeks pregnant is being treated for a pulmonary embolism. She has been receiving IV heparin per hospital protocol. 10,000 units of heparin have been infused. The nurse is called to the bedside urgently when the patient reports the passage of a large dark purple stool and some bright red blood with the bowel movement. The patient feels "like she might pass out." BP is 100/55, HR 110. Stat labs are run and the doctor on call decides that it's necessary to reverse the heparin immediately. Which would be an appropriate medication order from the physician on-call?
A) Vitamin K (phytonadione), 1 mg, IV, over 15 minutes.
B) protamine sulfate, 100 mg, IV, over 20 minutes.
C) Vitamin K, 1 mg, subQ, x1 dose.
D) Protamine sulfate, 1000 mg, IV, over 20 minutes.