A nurse is caring for a client who has COPD and has been taking fluticasone via inhaler for many years. Which of the following findings should the nurse identify as an adverse effect of long-term use of this medication?
A. Glomerular filtration rate (GFR) <60
B. Alanine aminotransferase (ALT) 82 units/L
C. Anorexia and weakness
D. Varicose veins in the lower extremities