Answer :

(genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism 

DNA replication is the process of producing two identical replicas from one original DNA molecule.
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Answer:

A mutation is a change that occurs in our DNA sequence, either due to mistakes when the DNA is copied or as the result of environmental factors such as UV light and cigarette smoke. Mutations can occur during DNA replication if errors are made and not corrected in time.