Answer :
The ottoman and Safavid war was a series of conflicts from 1623-1639 and the major conflict was related to land and control over Mesopotamia.
- Most of the conflicts between the two empires were related to land power and territory.
- From 1514 these two empires were engaged in conflicts over the control of South Caucasus and Mesopotamian as this area the two powerful states of West Asia. Their rivals were fueled by dogmatic differences.
Hence the option D is correct.
Learn more about the major source of conflict between the two empires.
brainly.com/question/5631903.