A. Given a 1:16 vinegar to water ratio, 1/4 cups of water would lead to 1/4*16=4 cups of water.
B. Using the same ratio, 80/16=5 fluid ounces of vinegar.
C. Again, using the ratio, 16 quarts of water will be added. This plus the quart of vinegar is a total of 17 quarts.
D. 1:16 is the vinegar to water ratio. Thus, for every 1 unit of vinegar, there will be 1+16=17 total units. Thus, the fraction is 1/17. Note that the spray bottle does not necessarily need to be full for this solution to work.