Answer :

Italy, Greece and France have never been under the Islamic Empire (or any Islamic rulers as far as I know).

Spain was under Islamic leaders for a long time and there was a period of re-conquista later, when the land was re-conquered by the Christians. And in 8th centrury Spain was in fact part of the Islamic Empire. 

Answer:

The answer is D: Spain

Explanation:

For a significant part of the Middle Ages, the Iberian Peninsula (modern-day Spain and Portugal) was ruled by the Islamic Empire. Muslims first arrived in 711 AD and ruled portions of the region until 1492. They had a significant impact on the culture and lives of the people in the region and brought many advancements to Europe.