Which of the following best explains why life expectancy among men trails that among women by about five years?
1) Men are less likely to die from accidents, cirrhosis of the liver, strokes, homicide, HIV/AIDS, cancer.
2) Hormonal differences between genders play a significant role.
3) Social and cultural factors lead to men seeking healthcare less frequently.
4) Genetic predispositions make men more susceptible to certain health conditions.