Which of the following reactions could be energetically coupled to the reaction Glucose + Pi- Glucose-6- Phosphate (-8.0 kcal/mol) to yield an overall thermodynamically favorable reaction?
1) AP → A + Pi (-4 kcal/mol)
2) B + Pi > BP (+7 kcal/mol)
3) CP → C + Pi (-10 kcal/mol)
4) DP > D + Pi (-9 kcal/mol)
5) E + Pi → EP (+9 kcal/mol)