The equation of the directrix of a parabola in the form (y-k)² = 4a(x-h) is x = h - a. In the given equation (y-3)² = 8(x-5), the vertex is at (5, 3) and the value of 'a' is 2 (since 4a = 8, giving a = 2).
Therefore, the equation of the directrix is x = 5 - 2, which simplifies to x = 3.
Hence, the correct answer is B. x = 3.