The statement provided is True. In the regeneration of a damaged nerve, Schwann cells indeed play a major role. Here's why:
1. Schwann cells release growth factors: These cells secrete growth factors that help stimulate the growth of axons, which are the long projections of nerve cells. By releasing these growth factors, Schwann cells create an environment that supports and promotes the regrowth of damaged nerve fibers.
2. Schwann cells form tubes to guide axonal growth: Schwann cells also form structures called "bands of Büngner," which act as physical guides or tunnels for regenerating axons to grow through. These tubes help direct the regenerating axons across the gap that forms when a nerve is damaged, assisting in the reconnection of the nerve fibers.
By releasing growth factors and forming guiding structures, Schwann cells actively participate in and support the process of nerve regeneration, making the statement True.
