The statement provided is True.
1. Opiate antagonists like naloxone and naltrexone indeed prevent opiates from acting in the synapses by binding to the opioid receptors without activating them. This blocks the effects of opiates, such as pain relief and feelings of euphoria.
2. These antagonists are commonly used in drug overdoses, particularly opioid overdoses, as they can quickly reverse the effects of the opioids by displacing them from the receptors and restoring normal breathing and consciousness.
3. In the context of helping recovering heroin addicts stay drug-free, these antagonists can be used to deter relapse. By blocking the effects of opioids, they reduce the rewarding sensations associated with drug use, making it less likely for individuals to relapse.
By understanding how opiate antagonists work to counteract the effects of opiates, we can see their crucial role in emergency situations like overdoses and in supporting individuals in overcoming opioid addiction.
