When using Purnell's Model for Cultural Competence to assess the biocultural ecology domain, the most appropriate question for the nurse to ask would be:
"Where were you born?"
This question directly relates to the biocultural ecology domain because it explores the individual's place of birth, which can provide valuable information about their biological and cultural background. By knowing where a person was born, the nurse can gain insights into their early environmental influences, family customs, language spoken at home, and potential health risks associated with certain regions. This question helps the nurse understand the interplay between biology and culture in shaping the individual's health beliefs and practices.