The ONLY definitive diagnostic test for Alzheimer's disease is:
1. Autopsy of the brain
Autopsy of the brain is currently the only way to definitively diagnose Alzheimer's disease. During an autopsy, pathologists can examine the brain tissue for the presence of characteristic markers of Alzheimer's, such as amyloid plaques and neurofibrillary tangles. These abnormalities are considered hallmarks of the disease and can only be accurately confirmed through post-mortem examination of the brain tissue.
While imaging studies like MRI and CT scans can provide supportive evidence for Alzheimer's disease by showing brain changes associated with the condition, they cannot definitively diagnose it. Similarly, blood tests are being researched for their potential to detect Alzheimer's-related biomarkers, but currently, they are not considered definitive diagnostic tools for the disease.
