What would be the effect on the membrane voltage of tripling the clamped current while
applying Rebine and capsaicin together to the nociceptor? You can click the VIEW IMAGE
button for help to answer the question.
a) Membrane voltage will remain constant
b) Membrane voltage will increase without an action potential occurring
c) The neuron would depolarize
d) Membrane voltage would decrease and an action potential will be observed
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Answer :

When tripling the clamped current while applying both Rebine and capsaicin to the nociceptor, the effect on the membrane voltage would lead to the neuron depolarizing. This means that the answer to the question is: c) The neuron would depolarize By increasing the clamped current, which essentially increases the flow of ions across the membrane, along with the presence of Rebine and capsaicin, which are known to modulate ion channels, the overall effect is the depolarization of the neuron. This depolarization can lead to changes in the membrane potential and potentially trigger an action potential. Therefore, the combination of increasing current, Rebine, and capsaicin would result in the depolarization of the neuron, affecting the membrane voltage and potentially leading to further neuronal signaling.