The primary adverse effect associated with some bisphosphonates is osteonecrosis. Bisphosphonates are a class of medications commonly used to treat osteoporosis and other bone-related conditions. Osteonecrosis is a serious condition where there is death of bone tissue due to poor blood supply. This can lead to pain, swelling, and in severe cases, the bone may collapse.
It is important to note that while osteonecrosis is a potential adverse effect of bisphosphonates, not everyone who takes these medications will experience this side effect. However, it is crucial for patients taking bisphosphonates to be aware of this risk and discuss any concerns with their healthcare provider. Regular dental check-ups are also recommended for those taking bisphosphonates as osteonecrosis of the jaw is a specific concern associated with these medications.