An oncogene is best described as a gene that promotes the division of cells with damaged DNA. These genes can cause normal cells to become cancerous by accelerating cell growth and division. When these oncogenes are mutated or overactive, they can lead to uncontrolled cell proliferation, which is a hallmark of cancer.
Conversely, tumor suppressor genes are genes that prevent cells with damaged DNA from dividing. These genes act as "brakes" on cell division and help maintain the integrity of the genome by either repairing the DNA damage or triggering cell death if the damage is too severe.
In summary, oncogenes promote the growth and division of cells with damaged DNA, while tumor suppressor genes inhibit the division of cells with damaged DNA to prevent the development of cancer.
