Answer:
Tinnitus
Explanation:
Many over-the-counter analgesic (pain relief) medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen (brand name Tylenol), COX-2 inhibitors (e.g. celecoxib, brand name Celebrex) are associated with an increased risk of developing tinnitus.
Tinnitus is a condition in which the patient's perceives a frequent ringing, buzzing, or roaring sound in the ears when no external source of noise is producing such. Though the exact cause is not well understood, it has been suggested by a 2010 study that the painkiller medications induce ototoxicity by reducing the motility of the hair cells in the inner ear responsible for amplifying sound, causing degeneration of ganglion neurons within the cochlea, and decreasing the compound action potential threshold in the eighth nerve (CN VIII, the vestibulocochlear nerve) thereby leading to hearing loss -- hearing loss is reported in about 10-25% of the people who experience tinnitus.
If a person taking painkillers experiences the adverse effect that is the ear disorder known as tinnitus, they should report this finding to the primary care provider as soon as possible so they can potentially switch to a different medication.