Chromosomal translocations involve the movement of genetic material between non-homologous chromosomes, as seen in the Philadelphia chromosome in chronic myeloid leukemia.
Translocations are chromosomal mutations where a segment from one chromosome attaches to a different chromosome. An example is the Philadelphia chromosome found in chronic myeloid leukemia, where chromosome 9 swaps with chromosome 22. This creates the BCR-ABL fusion protein, leading to uncontrolled white blood cell division.
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