Answer:
Option 1, onychomalacia
Explanation:
The root phrase and suffix that indicates the softening of an organ, surface, or tissue is -malacia, stemming from the Greek word malakos, which translates to soft.
The root phrase and prefix referring to specifically the nail(s) of the fingers and toes is onycho-, coming from the Greek word onyx, which originally meant claw, hoof, or talon.
Combining these two composes the medical term onychomalacia, option 1, the abnormal softening of the nail.
