Final answer:
Multidrug treatment for tuberculosis is essential to minimize the development of resistant strains and reduce adverse effects due to lower drug dosages.
Explanation:
The rationale that supports multidrug treatment for clients with tuberculosis includes:
- Multiple drugs reduce the development of resistant strains of the bacteria. Using a combination of drugs makes it harder for the bacteria to become resistant to all of them.
- Multiple drugs allow reduced drug dosages to be given. Lower dosages reduce adverse effects and improve tolerability.
- Multiple drugs reduce undesirable drug adverse effects. Different drugs can counteract each other's negative effects.
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