To inherit the disease hemophilia, which is X-linked, a male offspring would need to inherit the X-linked trait from his mother. This is because males inherit one X chromosome from their mother, as they receive a Y chromosome from their father, making the mother the carrier of the X-linked trait.
Therefore, for a male to have hemophilia:
- He needs to inherit the X-linked trait from his mother who is a carrier of the disease.
- If the father carries the hemophilia gene, he will pass on a Y chromosome to his son, not the X-linked trait for hemophilia.
In summary, in the case of hemophilia, a male offspring needs to inherit the X-linked trait from the mother to have the disease.
