¿Cuál de los siguientes causaría un error en la replicación del ADN?
Un. ADN ligasa que separa trozos de ADN
B. Emparejamiento de la ADN polimerasa C con G
C. Helicase haciendo una bifurcación de replicación
D. ADN polimerasa que comprueba el ADN



Answer :

To determine which of the options would cause an error in DNA replication, let's analyze each one:

A. ADN ligase que separa trozos de ADN:
- ADN ligase is responsible for sealing breaks in the sugar-phosphate backbone of DNA during replication and repair. If ADN ligase were to separate DNA fragments instead of sealing them, it would disrupt the continuity of the DNA strands, leading to errors in replication.

B. Emparejamiento de la ADN polimerasa C con G:
- The DNA polymerase should correctly pair nucleotides during replication. If DNA polymerase pairs C with G instead of the correct pairing (C with G and A with T), it would introduce mismatches in the newly synthesized DNA strand, causing errors.

C. Helicase haciendo una bifurcación de replicación:
- Helicase is responsible for unwinding the double-stranded DNA to create the replication fork. If helicase creates a replication fork in the wrong location or manner, it can lead to incomplete replication or the formation of abnormal DNA structures, resulting in errors.

D. ADN polimerasa que comprueba el ADN:
- The DNA polymerase has proofreading activity to check for errors in the newly synthesized DNA strand. If the DNA polymerase fails to perform this proofreading function effectively, mutations and mistakes can go unnoticed, leading to errors in DNA replication.

Therefore, out of the given options, option A, where ADN ligase separates DNA fragments instead of sealing them, would cause an error in DNA replication.

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