Answer: 15.5% guanine
1. According to Chargaff's rules, the number of cytosine molecules is always equal to the number of guanine molecules in a DNA strand.
If a DNA molecule has 15.5% cytosine, then according to Chargaff's rules, it will also have 15.5% guanine
2. If a DNA molecule has 21% adenine, it will also have 21% thymine. This is because the number of adenine molecules is always equal to the number of thymine molecules in a DNA strand.
Also, the total percentage of purines (adenine and guanine) is always equal to the total percentage of pyrimidines (cytosine and thymine) in a DNA molecule. So if there is 21% adenine, the percentage of guanine can be calculated as follows:
Let the percentage of guanine be x
Then, A% + G% = T% + C%
21% + x% = 21% + 15.5%
x% = 15.5%
Therefore, if a DNA molecule has 21% adenine, it will have 15.5% guanine.