Endochondral ossification is the process where cartilage is replaced by bone through the action of osteoblasts and osteoclasts.
Endochondral ossification is the process in which mineral deposits replace cartilage and change it into bone. During this process, blood vessels form in the cartilage, transporting osteoblasts and stem cells to convert the cartilage into bone tissue. Osteoblasts form a bone collar around the central shaft of the bone, while osteoclasts remove material from the center, forming the central cavity.
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