A 0.625 g of paracetamol powder with a uniformly sized particles was dissolved in 1000 ml of water. The dissolution data are found in the table below. Determine the value of k, the cube-root dissolution rate constant, at each time interval and calculate the average value of K. T(hr) Concent. Drug release mg/ml Amount drug release Mg/1lt Wt 0 159 Amount of undissolved drug Mt-625-Wt 0 0 0.159 466 4 0.288 0.39 288 337 6 8 390 235 0.468 0.528 468 157 10 528 97



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