Answer :

Final answer:

Long-term alcohol use can indeed lead to major depression due to its impacts on brain function and overall health.


Explanation:

True, long-term alcohol use can cause major depression. Excessive alcohol consumption can lead to alterations in brain function, nerve damage, and physiological addiction, contributing to mental health disorders such as major depressive disorder.

Alcoholism, characterized by addiction to ethanol, is a serious issue in the U.S., with heavy drinking impacting various organs including the liver and the cardiovascular system, ultimately shortening lifespan.

Multiple studies have shown the detrimental effects of chronic alcohol use on mental health, emphasizing the link between long-term alcohol consumption and the development of major depressive disorder.


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