Final answer:
Grapefruit juice enhances griseofulvin effects by inhibiting liver enzymes, leading to increased drug concentrations.
Explanation:
Grapefruit juice can increase the effects of griseofulvin by inhibiting CYP3A4 activity in the liver, leading to higher drug concentrations. This interaction occurs because grapefruit juice suppresses liver enzymes responsible for drug breakdown, potentially causing toxic levels of the drug in the body.
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