Final answer:
The Opium trade created conflicts between the Qing Dynasty and the British due to opium smuggling, leading to the Opium Wars.
Explanation:
Opium trade became a major issue of contention between the Qing Dynasty and the British. The British East India Company's trade and smuggling of opium to China led to the Opium Wars, where China eventually lost and was forced to open all its ports to foreign trade, including the trade in opium.
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