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The three main modes of transmission of pathogens, as described in the Chain of Infection model, are:

1. **Contact Transmission**: This occurs when pathogens are transferred from one person to another through direct or indirect contact. Direct contact involves physical contact between an infected person and a susceptible person, while indirect contact involves transfer via contaminated surfaces or objects.

2. **Droplet Transmission**: This mode of transmission involves the transfer of pathogens through respiratory droplets generated when an infected person coughs, sneezes, or talks. These droplets typically travel short distances and require close proximity between individuals for transmission.

3. **Airborne Transmission**: Pathogens are transmitted through the air over longer distances via small respiratory droplets or dust particles containing infectious agents. Airborne transmission can occur when an infected person exhales, coughs, or sneezes, leading to the inhalation of infectious particles by nearby individuals.

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