During inspiration, intrapleural pressure decreases, allowing air to flow into the lungs due to a pressure gradient.
Intrapleural pressure is the pressure in the pleural cavity and is always lower than intra-alveolar pressure. During inspiration, intrapleural pressure decreases further, creating a pressure gradient that allows air to flow into the lungs. Intrapulmonary pressure is lowest around mid-inspiration, facilitating the influx of air into the lungs.
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