Part 1: Categorizing a Genetic Disorder

How would you categorize a genetic disorder that is equally likely in males and females and is caused by the presence of two affected alleles?

A. Autosomal recessive disorder
B. Sex-linked disorder
C. Autosomal dominant disorder
D. Sex chromosome disorder

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Part 2: Nondisjunction of Autosomal Chromosomes

Nondisjunction of autosomal chromosomes, such as chromosome number 21, can result in disorders like:

A. Down syndrome
B. Klinefelter's syndrome
C. Turner's syndrome
D. Sickle-cell anemia

Nondisjunction in meiosis can lead to genetic disorders like Down syndrome. X chromosomes are more frequently involved in chromosomal disorders due to their size difference. Autosomal recessive disorders are equally likely in males and females.

Explanation:

Nondisjunction is the failure of replicated chromosomes to separate correctly during meiosis, leading to abnormal chromosome numbers. This can cause genetic disorders like Down syndrome when there is an extra chromosome 21 present.

Genetic disorders caused by abnormal chromosome numbers often involve the X chromosome because X and Y chromosomes are different in size, leading to more frequent nondisjunction events in sex chromosomes compared to autosomes.

Autosomal recessive disorders occur when two affected alleles are present, causing equally likely chances in males and females.

Learn more about genetic disorders here:

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