Match each changed nucleotide sequence to the correct type of mutation.

Original Nucleotide Sequence: CATTCACACA

Changed Nucleotide Sequences:
1. CATTCACACCACG
2. CATTTCACACG
3. CATTCACG
4. CATTECACAC

Types of Mutations:
A. Deletion
B. Insertion
C. Inversion
D. Duplication
E. Substitution



Answer :

In molecular biology, mutations refer to changes in the nucleotide sequence of an organism's DNA. Below, we'll align different types of mutations with given sequences as per the original nucleotide sequence `CATTCACACG`.

### Match the Types of Mutation:

Original Nucleotide Sequence:
```
CATTCACACG
```

Changed Nucleotide Sequences:
1. `cattcacaccacG`
2. `CATTTCACACG`
3. `CATTCACG`
4. `CATTECACAC`
5. `CATTCACACA`

#### Definitions of Mutations:
1. Deletion: A nucleotide is removed from the sequence.
2. Insertion: An extra nucleotide is added to the sequence.
3. Inversion: A portion of the sequence is reversed.
4. Duplication: A portion of the sequence is repeated.
5. Substitution: A nucleotide is replaced by a different nucleotide.

### Mutations Matched:

1. Deletion:
- Original: `CATTCACACG`
- Changed: `CATTCACG`
- Explanation: The nucleotide sequence `ACG` is deleted from the end of the original sequence.

2. Insertion:
- Original: `CATTCACACG`
- Changed: `cattcacaccacG`
- Explanation: The lowercase representation suggests an additional sequence `acacG` might be inserted within the original sequence.

3. Inversion:
- Original: `CATTCACACG`
- Changed: `CATTECACAC`
- Explanation: Assuming the typo in "ECAC" is an inversion of a portion of the sequence `ACA`, resulting in `ECA`.

4. Duplication:
- Original: `CATTCACACG`
- Changed: `CATTTCACACG`
- Explanation: Duplicate `T` within the original sequence `CAC.`

5. Substitution:
- Original: `CATTCACACG`
- Changed: `CATTTCACACG`
- Explanation: The third nucleotide `T` has been substituted with `C`.

### Final Matched Table:

| Type of Mutation | Original Nucleotide Sequence | Changed Nucleotide Sequence |
|------------------|------------------------------|-----------------------------|
| Deletion | CATTCACACG | CATTCACG |
| Insertion | CATTCACACG | cattcacaccacG |
| Inversion | CATTCACACG | CATTECACAC |
| Duplication | CATTCACACG | CATTCACACA |
| Substitution | CATTCACACG | CATTTCACACG |

Now, each sequence mutation is correctly matched with its type of mutation.