Answer :

Final answer:

Estrogen therapy can lead to thrombo-embolic disease, impacting blood circulation and potentially causing severe conditions like pulmonary embolism or stroke.


Explanation:

Thrombo-embolic disease can indeed be a complication of estrogen therapy. When a portion of a thrombus breaks free and enters the circulation, it can travel and block critical vessels, leading to conditions like pulmonary embolism or stroke. Estrogen therapy increasing the risk of thrombo-embolic events is a known concern in medical practice.


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